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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKN1B
All Species:
13.03
Human Site:
S112
Identified Species:
35.83
UniProt:
P46527
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46527
NP_004055.1
198
22073
S112
E
S
Q
D
V
S
G
S
R
P
A
A
P
L
I
Chimpanzee
Pan troglodytes
XP_522347
473
51257
R375
S
L
P
E
F
Y
Y
R
P
P
R
P
P
K
G
Rhesus Macaque
Macaca mulatta
XP_001085433
198
22067
S112
E
S
Q
D
V
S
G
S
R
P
A
A
P
L
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46414
197
22192
S112
E
S
Q
D
V
S
G
S
R
Q
A
V
P
L
I
Rat
Rattus norvegicus
NP_113950
197
22121
S112
E
S
L
D
V
S
G
S
R
Q
A
V
P
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989587
198
22242
N112
Q
S
L
D
V
N
G
N
C
Q
T
A
I
C
A
Frog
Xenopus laevis
NP_001087934
141
15992
R56
R
A
M
E
E
E
K
R
E
K
W
N
F
D
F
Zebra Danio
Brachydanio rerio
NP_997957
179
20267
R94
G
F
Y
S
R
S
E
R
G
K
G
S
D
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22197
184
21227
S99
P
L
S
S
P
S
T
S
D
K
E
E
P
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
98.4
N.A.
N.A.
87.8
87.3
N.A.
N.A.
68.6
29.7
41.4
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
100
35.9
98.9
N.A.
N.A.
92.9
91.4
N.A.
N.A.
78.7
44.4
58.5
N.A.
N.A.
N.A.
39.3
N.A.
P-Site Identity:
100
13.3
100
N.A.
N.A.
86.6
73.3
N.A.
N.A.
33.3
0
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
20
100
N.A.
N.A.
86.6
73.3
N.A.
N.A.
53.3
13.3
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
45
34
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% C
% Asp:
0
0
0
56
0
0
0
0
12
0
0
0
12
12
0
% D
% Glu:
45
0
0
23
12
12
12
0
12
0
12
12
0
0
0
% E
% Phe:
0
12
0
0
12
0
0
0
0
0
0
0
12
0
12
% F
% Gly:
12
0
0
0
0
0
56
0
12
0
12
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
45
% I
% Lys:
0
0
0
0
0
0
12
0
0
34
0
0
0
12
0
% K
% Leu:
0
23
23
0
0
0
0
0
0
0
0
0
0
34
12
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
0
12
0
0
0
% N
% Pro:
12
0
12
0
12
0
0
0
12
34
0
12
67
0
0
% P
% Gln:
12
0
34
0
0
0
0
0
0
34
0
0
0
0
0
% Q
% Arg:
12
0
0
0
12
0
0
34
45
0
12
0
0
0
0
% R
% Ser:
12
56
12
23
0
67
0
56
0
0
0
12
0
23
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
56
0
0
0
0
0
0
23
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
12
0
0
12
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _